John McLachlan John McLachlan, Professor of Pharmacology John McLachlan, Adjunct Professor of Ecology and Evolutionary Biology John McLachlan, Tulane University John McLachlan, Ph.D. Dr. John McLachlan John A. McLachlan John A. McLachlan, Tulane University School of Medicine John A. McLachlan, Endocrinology John A. McLachlan, Pharmacology Profesor John A. McLachlan, Endocrine Disruption


Dr. John McLachlan is Professor of Pharmacology, Adjunct Professor of Ecology and Evolutionary Biology, and Celia Scott Weatherhead & Albert J Weatherhead III Distinguished Professor of Environmental Studies at Tulane University. His research Interests include developmental pharmacology, toxicology and endocrinology, estrogen action and environmental estrogens, signaling, gene regulation, and gynecologic cancers.

Selected Publications

Journal of health care for the poor and underserved
In vitro and in vivo evaluation of novel anticancer agents in triple negative breast cancer models.
Johnson KP, Yearby LA, Stoute D, Burow ME, Rhodes LV, Gray M, Carriere P, Tilghman SL, McLachlan JA, Ochieng J.

Journal of Steroid Biochemistry and Molecular Biology
Antiestrogenic activity of flavonoid phytochemicals mediated via the c-Jun N-terminal protein kinase pathway. Cell-type specific regulation of estrogen receptor alpha.
Collins-Burow BM, Antoon JW, Frigo DE, Elliott S, Weldon CB, Boue SM, Beckman BS, Curiel TJ, Alam J, McLachlan JA, Burow ME.

Journal of Agricultural and Food Chemistry
Estrogenic and antiestrogenic activities of phytoalexins from red kidney bean.
Boué SM, Burow ME, Wiese TE, Shih BY, Elliott S, Carter-Wientjes CH, McLachlan JA, Bhatnagar D.

Journal of Medicinal Chemistry
Effects of 7-O substitutions on estrogenic and anti-estrogenic activities of daidzein analogues in MCF-7 breast cancer cells.
Jiang Q, Payton-Stewart F, Elliott S, Driver J, Rhodes LV, Zhang Q, Zheng S, Bhatnagar D, Boue SM, Collins-Burow BM, Sridhar J, Stevens C, McLachlan JA, Wiese TE, Burow ME, Wang G.

Environmental hormones: Multiple pathways for response may lead to multiple disease outcomes.
Tilghman SL, Nierth-Simpson EN, Wallace R, Burow ME, McLachlan JA.

Nature Protocols
Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing.
Crain DA, Janssen SJ, Edwards TM, Heindel J, Ho SM, Hunt P, Iguchi T, Juul A, McLachlan JA, Schwartz J, Skakkebaek N, Soto AM, Swan S, Walker C, Woodruff TK, Woodruff TJ, Giudice LC, Guillette LJ Jr.